Giants vs Tigers Live Stream: Start Time, Pitching Matchups, Lineups & Key Storylines

The San Francisco Giants head to Comerica Park on Monday, May 26 to open a three-game set against the first-place Detroit Tigers in a Memorial Day matinee that could serve as an early-season measuring stick for both clubs. Both teams enter with momentum. Detroit (34-20) sits atop the AL Central behind a pitching staff anchored by Cy Young front-runner Tarik Skubal, while San Francisco (31-22) has surged to second in the NL West thanks to a resurgent offense and lockdown bullpen. First pitch and pitching matchup • First pitch: 1:10 p.m. ET (12:10 p.m. local) • Probable starters: LHP Tarik Skubal (8-1, 1.86 ERA) vs. RHP Logan Webb (6-2, 2.48 ERA) Skubal has been nearly untouchable over his last eight starts, posting an 82/3 K/BB ratio while opponents hit just .184. Webb counters with a heavy sinker that has generated the league’s highest ground-ball rate since 2023. Key storylines to watch 1. Run prevention vs. power surge: Detroit owns MLB’s best team ERA (2.97), but the Giants have averaged 5.6 runs per game in May after inserting rookie mashers Marco Luciano and Luis Matos into the lineup. 2. Comerica Park conditions: Memorial Day forecasts call for a mild breeze blowing out to left-center, potentially aiding right-handed power threats like Spencer Torkelson and Michael Conforto. 3. Bullpen chess match: Detroit’s Jason Foley and Alex Faedo form a lights-out late-inning tandem, yet San Francisco has converted 18 of its last 19 save chances behind Camilo Doval. Lineup notes • The Tigers give rookie catcher Dillon Dingler his first big-league start, hoping to spark an offense that ranks 23rd in OPS vs. right-handed pitching. • Giants manager Bob Melvin confirmed Jorge Soler (oblique) remains day-to-day; Wilmer Flores is expected to DH. Recent head-to-head The clubs last met in 2023, when the Giants swept a two-game series in San Francisco by a combined score of 10-3. Detroit, however, took two of three the last time the venues shifted to Comerica in 2022. Odds, picks and prediction Sportsbooks list Detroit as a slight –120 favorite, with the over/under at 7.5 runs. Given the pitching duel, the under has value, but San Francisco’s right-handed bats match up well against Skubal’s fastball-slider mix. Prediction: Giants 4, Tigers 3. How to watch and stream • TV: NBC Sports Bay Area (Giants), Bally Sports Detroit • Streaming: MLB.tv, regional sports network apps (authentication required) • Radio: KNBR 680 (SF), 97.1 The Ticket (DET) Bottom line “Giants vs Tigers” may not evoke traditional rivalry, but this interleague clash pits two playoff hopefuls with contrasting blueprints. Whether you’re tracking Skubal’s dominance, Webb’s precision, or a potential fireworks show from Comerica’s spacious gaps, Monday’s opener promises can’t-miss afternoon baseball—and the winner could seize early momentum for the week ahead.