Buffalo Bills Depth Chart 2025: Latest Starter Updates, Surprising Roster Battles & Sleepers Revealed

The Buffalo Bills released their full 53-man roster and first official 2025 depth chart late Tuesday, giving fans and fantasy managers their clearest look yet at how Sean McDermott’s team will line up when they open the season. Below is a position-by-position breakdown, the biggest surprises, and what it all means for Week 1 and beyond. OFFENSE Quarterback 1. Josh Allen 2. Mitchell Trubisky Running Back / Fullback 1. James Cook 2. Ray Davis 3. Ty Johnson FB – Reggie Gilliam Wide Receiver X: Khalil Shakir │ Curtis Samuel (slot option) Z: Keon Coleman │ Joshua Palmer Depth: Elijah Moore, Tyrell Shavers Tight End 1. Dalton Kincaid 2. Dawson Knox 3. Jackson Hawes Offensive Line (LT-RT) Dion Dawkins, David Edwards, Connor McGovern, O’Cyrus Torrence, Spencer Brown Key reserves: Alec Anderson, Sedrick Van Pran-Granger, Chase Lundt, Ryan Van Demark DEFENSE Edge Rusher Greg Rousseau, Joey Bosa, A.J. Epenesa, Javon Solomon, Landon Jackson Defensive Tackle Ed Oliver, DaQuan Jones, T.J. Sanders, Deone Walker, DeWayne Carter Linebacker Terrel Bernard, Matt Milano, Dorian Williams, Joe Andreessen, Shaq Thompson Cornerback / Nickel Christian Benford, Tre’Davious White, Dorian Strong, Ja’Marcus Ingram, Taron Johnson (NB), Cam Lewis, Brandon Codrington Safety Taylor Rapp, Cole Bishop, Damar Hamlin, Jordan Hancock Specialists K Tyler Bass │ P Brad Robbins │ LS Reid Ferguson NOTABLE MOVES & INJURIES • Rookie CB Maxwell Hairston (shoulder) and OL Tylan Grable start on injured reserve with return designations. • DL Michael Hoecht and Larry Ogunjobi are suspended through Week 7. • Former Chargers star Joey Bosa slots opposite Rousseau, giving Buffalo its most formidable pass-rush duo since Mario Williams and Jerry Hughes. • Sixth-round pick Tyrell Shavers claimed the final WR spot after an impressive preseason finale. FANTASY & BETTING IMPACT • James Cook projects for a true three-down workload behind a rebuilt interior line and is a strong RB2 with RB1 upside in PPR leagues. • First-rounder Keon Coleman immediately steps into the vacated Gabe Davis role; his down-field profile makes him a late-round fantasy sleeper. • The addition of Bosa elevates the Bills D/ST back into top-five territory. WHAT’S NEXT The Bills host the Jacksonville Jaguars on Sept. 7. With Allen healthy, Cook primed for a breakout and the defense adding star power, Buffalo enters 2025 as an early AFC favorite. Expect weekly depth-chart tweaks, but Tuesday’s reveal solidifies key roles for the opener and sets the stage for the season’s first waiver-wire frenzy. Source: Buffalo Bills official 53-man roster announcement, Aug. 26, 2025